Title: dilution rate
Long Title: IUPAC Gold Book - dilution rate
DOI: 10.1351/goldbook.D01740
Status: current
Index: quantity

Definition
The ratio of the ingoing volume flow rate (\(\frac{\rm{d}V}{\rm{d}t}\)) and the culture volume (\(V\)). In continuous fermentation, a measure of a rate at which the existing medium is replaced with fresh medium, \(D\) is the reciprocal of the hydraulic retention time (\(\mathrm{HRT}\)).

Related Terms
- fermentation: https://dev.goldbook.iupac.org/terms/view/F02337
- volume flow rate: https://dev.goldbook.iupac.org/terms/view/V06642

Source
- PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 152 (https://doi.org/10.1351/pac199264010143)

Other Outputs
- html: https://dev.goldbook.iupac.org/terms/view/D01740/html
- json: https://dev.goldbook.iupac.org/terms/view/D01740/json
- xml: https://dev.goldbook.iupac.org/terms/view/D01740/xml

Citation: Citation: 'dilution rate' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.D01740
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .
Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-06-13T02:56:37+00:00