- The property of being nucleophilic.
- The relative reactivity of a nucleophilic reagent. (It is also sometimes referred to as 'nucleophilic power'.) Qualitatively, the concept is related to Lewis basicity. However, whereas Lewis basicity is measured by relative equilibrium constants:
N04251-1.png nucleophilicity of a Lewis base is measured by relative rate constants of different nucleophilic reagents towards a common substrate, most commonly involving formation of a bond to carbon:
See also: electrophilicity, Ritchie equation, Swain–Scott equation
PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1146 (https://doi.org/10.1351/pac199466051077)