Title: solvophobicity parameter
Long Title: IUPAC Gold Book - solvophobicity parameter
DOI: 10.1351/goldbook.S05763
Status: current
Index: quantity

Definition
A solvent parameter defined by: \[Sp = 1 - \frac{M}{M (\rm{hexadecane})}\] derived from the Gibbs energy of transfer (\(\Delta_{\rm{t}} G^{\circ}\)) of a series of solutes from water to numerous aqueous-organic mixtures and to pure solvents: \[\Delta_{\rm{t}} G^{\circ} ({\rm{to\ solvent}}) = M R_{\rm{T}} + D\] where \(R_{\rm{T}}\) is a solute parameter, and \(M\) and \(D\) characterize the solvent. The \(M\) values are used to define a solvent solvophobic effect so that \(Sp\) values are scaled from unity (water) to zero (hexadecane).

Related Term
- solvent parameter: https://dev.goldbook.iupac.org/terms/view/S05757

Source
- PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1165 (https://doi.org/10.1351/pac199466051077)

Other Outputs
- html: https://dev.goldbook.iupac.org/terms/view/S05763/html
- json: https://dev.goldbook.iupac.org/terms/view/S05763/json
- xml: https://dev.goldbook.iupac.org/terms/view/S05763/xml

Citation: Citation: 'solvophobicity parameter' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.S05763
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Accessed: 2026-06-13T02:54:36+00:00