Term: high-throughput screening https://doi.org/10.1351/goldbook.08177 Definition: Automated method to quickly assay large libraries of chemical species for the affinity of small organic molecules toward a target of interest. Note: Currently more than \(\pu{E5}\) different compounds can be tested per day. Source: PAC, 2022, 94, 353. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)' on page 431 (https://doi.org/10.1515/pac-2018-1010) Citation: 'high-throughput screening' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.08177 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.