Three-dimensional nuclear magnetic resonance spectroscopy for the assignment of protein structure with one carbon and two hydrogen dimensions.
Notes: - Magnetization is transferred from the side-chain hydrogen nuclei to their attached \(\ce{^{13}C}\) nuclei. This is followed by isotropic \(\ce{^{13}C}\) mixing and finally the transfer back to the side-chain hydrogen atoms for detection.
- The nuclear magnetic resonance spectrum is used for side-chain assignment.
See also: total correlation spectroscopy
Source:
PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 689 (https://doi.org/10.1515/pac-2019-0203)