Term: presaturation https://doi.org/10.1351/goldbook.08395 Definition: Technique to suppress a particular nuclear magnetic resonance spectroscopy signal where a long low-power pulse is applied to that specific resonance prior to the main pulse sequence. Note: Presaturation is typically used as a method for solvent suppression. Link: Related Term: nuclear magnetic resonance spectroscopy (http://doi.org/10.1351/goldbook.08218). Related Term: pulse sequence (http://doi.org/10.1351/goldbook.08396). Source: PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 700 (https://doi.org/10.1515/pac-2019-0203) Citation: 'presaturation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.08395 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.