Term: allosteric enzymes
https://doi.org/10.1351/goldbook.A00240

Definition:
enzymes which contain regions to which small, regulatory molecules (cf. effector) may bind in addition to and separate from substrate binding sites. On binding the effector, the catalytic activity of the enzyme towards the substrate may be enhanced, in which case the effector is an activator, or reduced, in which case it is an inhibitor.

Related Terms:
1) enzymes (http://doi.org/10.1351/goldbook.E02159).
2) effector (http://doi.org/10.1351/goldbook.E01901).
3) substrate (http://doi.org/10.1351/goldbook.S06083).
4) activator (http://doi.org/10.1351/goldbook.A00104).
5) inhibitor (http://doi.org/10.1351/goldbook.I03035).

Source: PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 146 (https://doi.org/10.1351/pac199264010143)

Citation: 'allosteric enzymes' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.A00240

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