Term: cine-substitution
https://doi.org/10.1351/goldbook.C01081

Definition:
A substitution reaction (generally aromatic) in which the entering group takes up a position adjacent to that occupied by the leaving group. For example, C01081.png

Related Terms:
1) tele-substitution (http://doi.org/10.1351/goldbook.T06256).
2) substitution reaction (http://doi.org/10.1351/goldbook.S06078).
3) aromatic (http://doi.org/10.1351/goldbook.A00441).
4) leaving group (http://doi.org/10.1351/goldbook.L03493).
5) entering group (http://doi.org/10.1351/goldbook.E02130).

Image: Not defined (https://goldbook.iupac.org/img/inline/C01081.png) 

Source: PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1097 (https://doi.org/10.1351/pac199466051077)

Citation: 'cine-substitution' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.C01081

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