Term: interstitial volume
https://doi.org/10.1351/goldbook.I03122

Definition:
The volume V G of the column not occupied by the liquid phase and its solid support, or by the active solid. It does not include any volume external to the column, such as the volume of the sample injector or of the detector.

Related Terms:
1) active solid (http://doi.org/10.1351/goldbook.A00109).

Source: Orange Book, 2nd ed., p. 99 (https://media.iupac.org/publications/analytical_compendium/)

Citation: 'interstitial volume' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.I03122

License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.

Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.