Term: isotopic scrambling https://doi.org/10.1351/goldbook.I03348 Definition: The achievement, or the process of achieving, an equilibrium distribution of isotopes within a specified set of atoms in a chemical species or group of chemical species (for an example, see diagram). I03348-1.png I03348-2.png Related Terms: 1) fractionation factor (http://doi.org/10.1351/goldbook.I03343). 2) isotopes (http://doi.org/10.1351/goldbook.I03331). Images: 1) Not defined (https://goldbook.iupac.org/img/inline/I03348-1.png) 2) Not defined (https://goldbook.iupac.org/img/inline/I03348-2.png) Source: PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1132 (https://doi.org/10.1351/pac199466051077) Citation: 'isotopic scrambling' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.I03348 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.