Term: isotopomer https://doi.org/10.1351/goldbook.I03352 Definition: Isomers having the same number of each isotopic atom but differing in their positions. The term is a contraction of 'isotopic isomer'. Isotopomers can be either constitutional isomers (e.g. CH2DCH=O and CH3CD=O) or isotopic stereoisomers [e.g. (R)- and (S)-CH3CHDOH or (Z)- and (E)-CH3CH=CHD]. Related Terms: 1) isomer (http://doi.org/10.1351/goldbook.I03289). 2) stereoisomers (http://doi.org/10.1351/goldbook.S05984). Source: PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1132 (https://doi.org/10.1351/pac199466051077) Citation: 'isotopomer' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.I03352 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.