Term: polyelectrolyte https://doi.org/10.1351/goldbook.P04728 Definition: Polymer composed of macromolecules in which a substantial portion of the constitutional units contains ionic or ionizable groups, or both. Notes: 0) The terms polyelectrolyte, polymer electrolyte, and polymeric electrolyte should not be confused with the term @ST07227@. 1) Polyelectrolytes can be either synthetic or natural. @N04245@, @P04898@, teichoic acids, some @P04749@, and some @P04752@ are examples of natural polyelectrolytes. Related Terms: 1) solid polymer electrolyte (http://doi.org/10.1351/goldbook.ST07227). 2) nucleic acids (http://doi.org/10.1351/goldbook.N04245). 3) proteins (http://doi.org/10.1351/goldbook.P04898). 4) polypeptides (http://doi.org/10.1351/goldbook.P04749). 5) polysaccharides (http://doi.org/10.1351/goldbook.P04752). Source: PAC, 2006, 78, 2067. 'Terminology of polymers containing ionizable or ionic groups and of polymers containing ions (IUPAC Recommendations 2006)' on page 2072 (https://doi.org/10.1351/pac200678112067) Citation: 'polyelectrolyte' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.P04728 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.