Term: probe
https://doi.org/10.1351/goldbook.P04857

Definition:
A specific DNA or RNA sequence which has been labelled by radioactivity, fluorescence labels or chemiluminescence labels and which is used to detect complementary sequences by hybridization techniques such as blotting or colony hybridization.

Related Terms:
1) dna (http://doi.org/10.1351/goldbook.D01597).
2) rna (http://doi.org/10.1351/goldbook.R05386).
3) hybridization (<em>in biotechnology</em>) (http://doi.org/10.1351/goldbook.H02874).
4) blotting (<em>in biotechnology</em>) (http://doi.org/10.1351/goldbook.B00686).
5) sequence (http://doi.org/10.1351/goldbook.ST06775).
6) radioactivity (http://doi.org/10.1351/goldbook.R05092).
7) fluorescence (http://doi.org/10.1351/goldbook.F02453).
8) chemiluminescence (http://doi.org/10.1351/goldbook.C01045).

Source: PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 163 (https://doi.org/10.1351/pac199264010143)

Citation: 'probe' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.P04857

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