A technique used to produce proteins with altered or novel amino acid sequences. The methods used are:
- Transcription and translation systems from synthesized lengths of DNA or RNA with novel sequences.
- Chemical modification of 'normal' proteins.
- Solid-state polypeptide synthesis to form proteins.
PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 163 (https://doi.org/10.1351/pac199264010143)