Partial least squares projection to latent structures (
PLS) is a robust multivariate generalized regression method using projections to summarize multitudes of potentially collinear variables.
Source:
PAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1148 (https://doi.org/10.1351/pac199769051137)