Term: polymer-supported reaction https://doi.org/10.1351/goldbook.PT07147 Definition: Chemical reaction in which at least one reactant or a catalyst is bound through chemical bonds or weaker interactions, such as hydrogen bonds or donor–acceptor interactions, to a polymer. Notes: 0) The easy separation of low-molar-mass reactants or products from the polymer-supported species is a great advantage of polymer-supported reactions. 1) Typical examples of polymer-supported reactions are: (a) reactions performed by use of polymer-supported catalysts, (b) solid-phase peptide synthesis, in which intermediate peptide molecules are chemically bonded to beads of a suitable @PT07191@. Related Terms: 1) polymer support (http://doi.org/10.1351/goldbook.PT07191). 2) catalyst (http://doi.org/10.1351/goldbook.C00876). Source: PAC, 2004, 76, 889. 'Definitions of terms relating to reactions of polymers and to functional polymeric materials (IUPAC Recommendations 2003)' on page 894 (https://doi.org/10.1351/pac200476040889) Citation: 'polymer-supported reaction' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.PT07147 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.