restriction enzymes

https://doi.org/10.1351/goldbook.R05350
Endonucleases which recognize specific base sequences within a DNA helix, creating a double-strand break of DNA. Type I restriction enzymes bind to these recognition sites but subsequently cut the DNA at different sites. Type II restriction enzymes both bind and cut within their recognition or target sites.
Source:
PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 164 (https://doi.org/10.1351/pac199264010143)