Term: solid support https://doi.org/10.1351/goldbook.S05737 Definition: Normally an inert porous solid, which sorbs the liquid phase. The particle-size range of the support affects column efficiency and the pressure differential necessary to achieve a given flow rate. Modifications have been introduced for the achievement of special separations, in which the solid support is not inert but is an active solid. In capillary columns the inner wall of the column serves as the solid support and obviates the use of additional porous solids for this purpose. Related Terms: 1) inert (http://doi.org/10.1351/goldbook.I03026). 2) active solid (http://doi.org/10.1351/goldbook.A00109). Source: Orange Book, 2nd ed., p. 98 (https://media.iupac.org/publications/analytical_compendium/) Citation: 'solid support' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.S05737 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.