Term: stereospecificity (stereospecific)
https://doi.org/10.1351/goldbook.S05994

Definition:
A reaction is termed stereospecific if starting materials differing only in their configuration are converted into stereoisomeric products. According to this definition, a stereospecific process is necessarily stereoselective but not all stereoselective processes are stereospecific. Stereospecificity may be total (100%) or partial. The term is also applied to situations where reaction can be performed with only one stereoisomer. For example, the exclusive formation of trans-1,2-dibromocyclohexane upon bromination of cyclohexene is a stereospecific process, although the analogous reaction with (E)-cyclohexene has not been performed.

Related Terms:
1) configuration (http://doi.org/10.1351/goldbook.C01249).
2) stereoselective (http://doi.org/10.1351/goldbook.S05991).
3) trans (http://doi.org/10.1351/goldbook.C01092).

Source: 

Citation: 'stereospecificity (stereospecific)' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.S05994

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