Term: tele-substitution https://doi.org/10.1351/goldbook.T06256 Definition: A substitution reaction in which the entering group takes up a position more than one atom away from the atom to which the leaving group was attached: T06256.png Related Terms: 1) cine-substitution (http://doi.org/10.1351/goldbook.C01081). 2) substitution reaction (http://doi.org/10.1351/goldbook.S06078). 3) entering group (http://doi.org/10.1351/goldbook.E02130). 4) leaving group (http://doi.org/10.1351/goldbook.L03493). Image: Not defined (https://goldbook.iupac.org/img/inline/T06256.png) Source: PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1172 (https://doi.org/10.1351/pac199466051077) Citation: 'tele-substitution' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.T06256 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.