Term: universal calibration
https://doi.org/10.1351/goldbook.U06564

Definition:
A calibration of a size-exclusion chromatography set-up based on the finding that the retention volume of a molecular or particulate species is a single-valued function of an appropriate size parameter of this molecule or particle, irrespective of its chemical nature and structure. The product of the intrinsic viscosity and molar mass, [η]M, has been widely used as the size parameter.

Related Terms:
1) size-exclusion chromatography (http://doi.org/10.1351/goldbook.S05705).
2) intrinsic viscosity (<em>of a polymer</em>) (http://doi.org/10.1351/goldbook.I03140).

Source: Purple Book, 1st ed., p. 69 (http://old.iupac.org/publications/books/author/metanomski.html)

Citation: 'universal calibration' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.U06564

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