halogen bond

https://doi.org/10.1351/goldbook.08173
Association between a Lewis-acidic halogen atom in a molecular entity and a Lewis-basic region in another, or the same, molecular entity, which acts as an electron-pair donor, such that the balance of forces of attraction and repulsion results in net stabilization.
Notes:
  1. Typical halogen-bond donors are IA2, BrA2, ICN, and IC≡CH.
  2. This is analogous to a hydrogen bond, in which the H is the acidic atom.
  3. The interaction provides a stabilization of a few kJmol−1.
Source:
PAC, 2022, 94, 353. (Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)) on page 427 [Terms] [Paper]
Citation: 'halogen bond' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.08173 RIS BibTex EndNote
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