desorption electrospray ionization mass spectrometry

acronym: DESI
https://doi.org/10.1351/goldbook.09181
Measurement method in which a mass spectrometer is used to measure the ratio of mass to charge and the abundance of ionized entities emitted from a sample in air as a result of the bombardment by ionized solvent droplets generated by pneumatically assisted electrospray ionization.
Notes:
  1. Water and methanol are often used as the solvents to create the droplets. Acids and alkalis are added to control the solution pH.
  2. DESI is one of the few surface analysis methods designed to analyse materials without exposure to vacuum. It is used for complex molecules, organic molecules, and biomolecules. In vivo analysis is claimed to be possible.
Source:
PAC, 2020, 92, 1781. (Glossary of methods and terms used in surface chemical analysis (IUPAC Recommendations 2020)) on page 1786 [Terms] [Paper]
Citation: 'desorption electrospray ionization mass spectrometry' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09181 RIS BibTex EndNote
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