cooperativity

https://doi.org/10.1351/goldbook.C01325
Interaction between the
substrate
binding sites of an
allosteric enzyme
. Binding of a substrate molecule to one
binding site
changes the affinity of the binding sites on the other subunits (cf.
allosteric enzyme
) to the substrate by induction of a
conformation
change at the other binding sites. Cooperative
enzymes
typically display a sigmoid (S-shaped) plot of the reaction rate against substrate concentration.
Source:
PAC, 1992, 64, 143. (Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)) on page 151 [Terms] [Paper]