cytochrome P450

https://doi.org/10.1351/goldbook.CT06821
Member of a superfamily of heme-containing monooxygenases involved in xenobiotic metabolism, cholesterol biosynthesis, and steroidogenesis, in eukaryotic organisms found mainly in the endoplasmic reticulum and inner mitochondrial membrane of cells. ‘P450’ refers to a feature in the carbon monoxide absorption difference spectrum at 450 nm caused by the presence of a thiolate in the axial position of the heme opposite to the carbon monoxide ligand.
Source:
PAC, 2004, 76, 1033. (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1048 [Terms] [Paper]
Citation: 'cytochrome P450' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.CT06821 RIS BibTex EndNote
Div. VIIPDFTextXMLJSON
Last revised: February 24, 2014