A point
mutation involving either the deletion or
insertion of a
nucleotide in a
gene. By the frame-shift
mutation, the normal
reading frame used when decoding the nucleotide triplets in the gene is altered to another
reading frame.
Source: PAC, 1992,
64, 143. (
Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)) on page 154 [
Terms] [
Paper]