first-pass effect

https://doi.org/10.1351/goldbook.FT06824
@B00667@ and, in some cases, @E02038@ of a substance in the liver after absorption from the intestine and before it reaches the @ST06802@ circulation.
Source:
PAC, 2004, 76, 1033. (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1052 [Terms] [Paper]
Citation: 'first-pass effect' in IUPAC Compendium of Chemical Terminology, 3rd ed. International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. https://doi.org/10.1351/goldbook.FT06824 RIS BibTex EndNote
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Last revised: February 24, 2014