Hansch constant

https://doi.org/10.1351/goldbook.H02736
A measure of the capability of a solute for hydrophobic lipophilic interaction based on the partition coefficient P for distribution of the solute between octan-1-ol and water. The most general way of applying P in correlation analysis, QSAR, etc. is as log P, but the behaviour of substituted benzene derivatives may be quantified by a substituent constant scale, π, which is defined in a way analogous to the Hammett σ scale. There are various scales, depending on the substrate series used as reference.
Source:
PAC, 1994, 66, 1077. (Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)) on page 1119 [Terms] [Paper]
Citation: 'Hansch constant' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.H02736 RIS BibTex EndNote
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Last revised: October 7, 2008