leader sequence

in biotechnology
Also contains definition of: signal sequence
https://doi.org/10.1351/goldbook.L03491
  1. A polynucleotide region between
    promoter
    and structural
    gene
    , necessary for the correct
    transcription
    of
    DNA
    into
    mRNA
    .
  2. An N-terminal extension of
    polypeptides
    (also known as the signal sequence) which is necessary for the transport of the
    protein
    into or through the
    membrane
    or for its secretion into the extracellular medium.
Source:
PAC, 1992, 64, 143. (Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)) on page 158 [Terms] [Paper]