https://doi.org/10.1351/goldbook.L03540
The limit of detection, expressed as the concentration, cL, or the quantity, qL, is derived from the smallest measure, xL, that can be detected with reasonable certainty for a given analytical procedure. The value of xL is given by the equation xL=xbi+k sbi where xbi is the mean of the blank measures, sbi is the
standard deviation
of the blank measures, and k is a numerical factor chosen according to the
confidence level
desired.
Source:
Orange Book, 2nd ed., p. 5 [Terms] [Book]