phase I reaction

of biotransformation
https://doi.org/10.1351/goldbook.PT06836
Enzymic modification of a substance by oxidation, reduction, hydrolysis, hydration, dehydrochlorination, or other reactions catalyzed by enzymes of the cytosol, of the endoplasmic reticulum (microsomal enzymes) or of other cell organelles.
Source:
PAC, 2004, 76, 1033. (Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)) on page 1064 [Terms] [Paper]
Citation: 'phase I reaction' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.PT06836 RIS BibTex EndNote
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Last revised: February 24, 2014