distortion interaction model 

Synonym: activation strain model
https://doi.org/10.1351/goldbook.08163
Method for analyzing activation energy as the sum of the energies to distort the reactants into the geometries they have in transition states plus the energy of interaction between the two distorted reactants.
Source:
PAC, 2022, 94, 353. (Glossary of terms used in physical organic chemistry (IUPAC Recommendations 2021)) on page 405 [Terms] [Paper]
Citation: 'distortion interaction model' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.08163 RIS BibTex EndNote
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