15N-TOCSY-HSQC

https://doi.org/10.1351/goldbook.08309

Three-dimensional nuclear magnetic resonance spectroscopy for the assignment of protein structure with one nitrogen and two hydrogen dimensions.

Note: An isotropic mixing step transfers magnetization between A1A221H spins. Then the magnetization is transferred to neighbouring A15A2215N nuclei and back to A1A221H for detection. This can help identify amino acid types.
See also: total correlation spectroscopy
Source:
PAC, 2021, 93, 647. (Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)) on page 680 [Terms] [Paper]
Citation: '15N-TOCSY-HSQC' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.08309 RIS BibTex EndNote
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