https://doi.org/10.1351/goldbook.C01480
In a ) of the respective
It is also true that the product composition is formally related to the relative concentrations of the conformational isomers A' and A'' (i.e. the conformational
chemical reaction
that yields one product (X) from one conformational isomer
(A') and a different product (Y) from another conformational isomer
(A'') (and provided these two isomers are rapidly interconvertible relative to the rate of product formation, whereas the products do not undergo interconversion) the product composition is not in direct proportion to the relative concentrations of the conformational isomers in the substrate
; it is controlled only by the difference in standard free energies (transition states
. ![Not defined](/img/inline/C01480-1.png)
equilibrium constant
) and the respective rate constants of their reactions; these parameters are generally — though not invariably — unknown. The diagram below represents the energetic situation for transformation
of interconverting isomers A and A' into products X and Y. ![Not defined](/img/inline/C01480.png)